1/2/2024 0 Comments Netspot radiopharmaceutical![]() ![]() Safety and Efficacy of 68Ga-DOTATATE PET/CT for Diagnosis, Staging, and Treatment Management of Neuroendocrine Tumors. ![]() Deppen SA, Liu E, Blume JD, Clanton J, Shi C, Jones-Jackson LB, Lakhani V, Baum RP, Berlin J, Smith GT, Graham M, Sandler MP, Delbeke D, Walker RC. The salivary glands and thyroid show faint to mild homogeneous uptake 4,5. There is normal Ga-68 DOTATATE uptake in the pituitary gland, spleen, liver, adrenal glands, and urinary tract 4,5. These have an affinity for different somatostatin receptors, SSTR subtypes 3 and 5 and SSTR subtype 5, respectively 3. It binds SSTR subtype 2 and binds 100 times more avidly than indium-111 pentetreotide 2. Ga-68 DOTATATE has shown improved accuracy for detection relative to indium-111 pentetreotide SPECT-CT 1.
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